The levels of expression of galectin-1, galectin-3, and the Thomsen-Friedenreich antigen and their binding sites decrease as clinical aggressiveness increases in head and neck cancers.

@article{Choufani1999TheLO,
  title={The levels of expression of galectin-1, galectin-3, and the Thomsen-Friedenreich antigen and their binding sites decrease as clinical aggressiveness increases in head and neck cancers.},
  author={Georges Choufani and Nathalie Nagy and Sven Saussez and Horace G. Marchant and Peter De Bisschop and Marta Burchert and Andr{\'e} Danguy and St{\'e}phane Louryan and Isabelle Salmon and Hans Joachim Gabius and R{\'o}bert Kiss and Sergio Hassid},
  journal={Cancer},
  year={1999},
  volume={86 11},
  pages={2353-63}
}
BACKGROUND The aim of this study was to investigate whether an increase in malignancy level is accompanied by significant modifications of the expression of galectin-1, galectin-3, and Thomsen-Friedenreich antigen (T antigen) as well as the expression of binding sites for these three markers in head and neck squamous cell carcinomas (HNSCCs). METHODS Immunohistochemical and glycohistochemical staining reactions were carried out with antibodies, labeled lectins, and a custom-made… CONTINUE READING

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