The let-7 microRNA directs vulval development through a single target.

Abstract

The let-7 microRNA (miRNA) regulates stemness in animals ranging from worms to humans. However, the cause of the dramatic vulval rupturing phenotype of let-7 mutant C. elegans has remained unknown. Consistent with the notion that miRNAs function by coordinately tuning the expression of many targets, bursting may result from joint dysregulation of several… (More)
DOI: 10.1016/j.devcel.2014.12.018

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Cite this paper

@article{Ecsedi2015TheLM, title={The let-7 microRNA directs vulval development through a single target.}, author={Matyas Ecsedi and Magdalene Rausch and Helge Gro\sshans}, journal={Developmental cell}, year={2015}, volume={32 3}, pages={335-44} }