The lens has a specific influence on optic nerve and tectum development in the blind cavefish Astyanax.

@article{Soares2004TheLH,
  title={The lens has a specific influence on optic nerve and tectum development in the blind cavefish Astyanax.},
  author={Daphne Soares and Yoshiyuki Yamamoto and Allen G. Strickler and William R Jeffery},
  journal={Developmental neuroscience},
  year={2004},
  volume={26 5-6},
  pages={308-17}
}
We used the teleost Astyanaxmexicanus to examine the role of the lens in optic nerve and tectum development. This speciesis unusually suited for studies of nervous system development and evolution because of its two extant forms: an eyed surface dwelling (surface fish) and several blind cave dwelling (cavefish) forms. Cavefish embryos initially form eye primordia, but the lens eventually dies by apoptosis, then the retina ceases to grow, and finally the degenerating eyes sink into the orbits… CONTINUE READING