The lateral habenula in addiction and depression: an anatomical, synaptic and behavioral overview.

@article{Lecca2014TheLH,
  title={The lateral habenula in addiction and depression: an anatomical, synaptic and behavioral overview.},
  author={Salvatore Lecca and Frank J Meye and Manuel Mameli},
  journal={The European journal of neuroscience},
  year={2014},
  volume={39 7},
  pages={1170-8}
}
The lateral habenula (LHb) is an epithalamic region with a crucial role in the regulation of midbrain monoaminergic systems. Over the past few years a renewed interest in the LHb has emerged due to studies highlighting its central role in encoding rewarding and aversive aspects of stimuli. Moreover, an increasing number of functional as well as behavioral indications provide substantial evidence supporting a role of LHb in neuropsychiatric diseases, including mood disorders and drug addiction… CONTINUE READING