The latent reservoir for HIV-1 in resting CD4+ T cells: a barrier to cure.

@article{Siliciano2006TheLR,
  title={The latent reservoir for HIV-1 in resting CD4+ T cells: a barrier to cure.},
  author={Janet D Siliciano and Robert F. Siliciano},
  journal={Current opinion in HIV and AIDS},
  year={2006},
  volume={1 2},
  pages={121-8}
}
PURPOSE OF REVIEW Despite remarkable progress in the development of drugs that inhibit HIV-1 replication, eradication of the infection has not been achieved. The principal reason is that the virus can persist in stable cellular reservoirs, the best characterized of which is a small pool of latently infected resting memory CD4 T cells that carry a stably… CONTINUE READING