The large-scale organization of metabolic networks

  title={The large-scale organization of metabolic networks},
  author={H. Jeong and B. Tombor and R. Albert and Z. Oltvai and A.-L. Barab{\'a}si},
  • H. Jeong, B. Tombor, +2 authors A.-L. Barabási
  • Published 2000
  • Computer Science, Medicine, Physics, Biology
  • Nature
  • In a cell or microorganism, the processes that generate mass, energy, information transfer and cell-fate specification are seamlessly integrated through a complex network of cellular constituents and reactions. However, despite the key role of these networks in sustaining cellular functions, their large-scale structure is essentially unknown. Here we present a systematic comparative mathematical analysis of the metabolic networks of 43 organisms representing all three domains of life. We show… CONTINUE READING
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