The large-X effect in plants: increased species divergence and reduced gene flow on the Silene X-chromosome.

@article{Hu2016TheLE,
  title={The large-X effect in plants: increased species divergence and reduced gene flow on the Silene X-chromosome.},
  author={Xin-Sheng Hu and Dmitry A. Filatov},
  journal={Molecular ecology},
  year={2016},
  volume={25 11},
  pages={
          2609-19
        }
}
The disproportionately large involvement of the X-chromosome in the isolation of closely related species (the large-X effect) has been reported for many animals, where X-linked genes are mostly hemizygous in the heterogametic sex. The expression of deleterious recessive mutations is thought to drive the frequent involvement of the X-chromosome in hybrid sterility, as well as to reduce interspecific gene flow for X-linked genes. Here, we evaluate the role of the X-chromosome in the speciation of… CONTINUE READING
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Counterselection on sex-chromosomes in the Mus musculus European hybrid zone

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