The landscape of histone acetylation involved in epithelial-mesenchymal transition in lung cancer.

@article{Zhang2013TheLO,
  title={The landscape of histone acetylation involved in epithelial-mesenchymal transition in lung cancer.},
  author={Lin Zhang and Zuogong Liu and W. T. Ma and Bin Wang},
  journal={Journal of cancer research and therapeutics},
  year={2013},
  volume={9 Suppl 2},
  pages={S86-91}
}
Epithelial-mesenchymal transition (EMT) has been widely accepted as the early stage of tumor metastasis, which is accomplished by a group of transcription factors based on cancer genome. However, with the progress of epigenome profiling technique, it has been demonstrated that aberrant histone modifications especially acetylation play an important role in EMT and cancer metastasis. Besides this, numerous studies have elucidated the mechanisms of histone acetyltransferases and deacetylases… CONTINUE READING