The lambda repressor contains two domains.

@article{Pabo1979TheLR,
  title={The lambda repressor contains two domains.},
  author={Carl O. Pabo and Robert T. Sauer and Julian M. Sturtevant and Mark Ptashne},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1979},
  volume={76 4},
  pages={1608-12}
}
Papain digestion of the lambda phage repressor produces two fragments that are relatively resistant to further digestion. One includes the amino terminus (residues 1-92) and the other the carboxyl terminus (residues 132-236). Calorimetry shows that the amino-terminal fragment denatures near 50 degrees C and that the carboxyl-terminal fragment denatures near 70 degrees C. Intact repressor undergoes two denaturations, one near 50 degrees C and another near 70 degrees C. These and other data show… CONTINUE READING

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