The king is dead (warfarin): direct thrombin and factor Xa inhibitors: the next Diadochian War?

@article{Diener2012TheKI,
  title={The king is dead (warfarin): direct thrombin and factor Xa inhibitors: the next Diadochian War?},
  author={Hans-Christoph Diener and John W. Eikelboom and Christopher B. Granger and Werner Hacke},
  journal={International journal of stroke : official journal of the International Stroke Society},
  year={2012},
  volume={7 2},
  pages={139-41}
}
Atrial fibrillation is an important risk factor for stroke. New drugs for oral anticoagulation that do not exhibit the limitations of vitamin K antagonists like warfarin are under investigation. These include direct factor Xa inhibitors and direct thrombin-inhibitors. Recent studies provide promising results for apixaban, dabigatran, and rivaroxaban… CONTINUE READING