The kinetics of nifedipine release from porous hydrophilic matrices and the pharmacokinetics in man.

@article{Leucua1988TheKO,
  title={The kinetics of nifedipine release from porous hydrophilic matrices and the pharmacokinetics in man.},
  author={Sorin Emilian Leucuţa},
  journal={Die Pharmazie},
  year={1988},
  volume={43 12},
  pages={845-8}
}
Porous hydrophilic tablets of nifedipine were prepared with hydroxypropyl methylcellulose as swellable polymer, as well as with the addition of a solid dispersion of the drug in polyethylene glycol, a water soluble system. The kinetic data conformed with the Higuchi square root equation and first order release for in vitro release from a single planar… CONTINUE READING