The kinetics of cytokine mRNA expression in the retina during experimental autoimmune uveoretinitis.

@article{Barton1995TheKO,
  title={The kinetics of cytokine mRNA expression in the retina during experimental autoimmune uveoretinitis.},
  author={Keith Barton and Mark McLauchlan and Virginia L Calder and Susan L. Lightman},
  journal={Cellular immunology},
  year={1995},
  volume={164 1},
  pages={
          133-40
        }
}
Experimental autoimmune uveoretinitis (EAU) was induced in Lewis rats and the inflamed retinas were examined for IFN-gamma, IL-2, IL-4, and IL-10 mRNA production at serial time points using the reverse transcriptase-polymerase chain reaction. IFN-gamma, IL-2, IL-4, and IL-10 mRNAs were all detected 24 hr before the earliest time point at which histological changes have previously been detected. IFN-gamma, IL-2, and IL-4 mRNA expression peaked during the active phase of the disease and declined… CONTINUE READING
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