The kinetics and rectifier properties of the slow potassium current in cardiac Purkinje fibres.

@article{Noble1968TheKA,
  title={The kinetics and rectifier properties of the slow potassium current in cardiac Purkinje fibres.},
  author={Denis Noble and Richard W. Tsien},
  journal={The Journal of physiology},
  year={1968},
  volume={195 1},
  pages={185-214}
}
1. The reversal potential of the slow outward current in Purkinje fibres varies with [K](o) in accordance with the expected potassium equilibrium potential. It is concluded that virtually all of this current is carried by potassium ions.2. The magnitude of the current is determined by two separable factors. The first factor is directly proportional to a variable obeying first-order voltage-dependent kinetics of the Hodgkin-Huxley type but with extremely long time constants. The time constants… CONTINUE READING

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