The kinesin-like protein CENP-E is kinetochore-associated throughout poleward chromosome segregation during anaphase-A.

Abstract

The kinesin-like protein CENP-E transiently associates with kinetochores following nuclear envelope breakdown in late prophase, remains bound throughout metaphase, but sometime after anaphase onset it releases and by telophase becomes bound to interzonal microtubules of the mitotic spindle. Inhibition of poleward chromosome movement in vitro by CENP-E… (More)

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