The key role for local base order in the generation of multiple forms of China HIV-1 B'/C intersubtype recombinants

@article{Zhang2005TheKR,
  title={The key role for local base order in the generation of multiple forms of China HIV-1 B'/C intersubtype recombinants},
  author={Chiyu Zhang and Ji-Fu Wei and Shaoheng He},
  journal={BMC Evolutionary Biology},
  year={2005},
  volume={5},
  pages={53 - 53}
}
HIV-1 is a retrovirus with high rate of recombination. Increasing experimental studies in vitro indicated that local hairpin structure of RNA was associated with recombination by favoring RT pausing and promoting strand transfer. A method to estimate the potential to form stem-loop structure by calculating the folding of randomized sequence difference (FORS-D) has been used to investigate the relationship between secondary structure and evolutionary pressure in some genome. It showed that gene… CONTINUE READING

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Conservation of Stem-Loop Potential in Introns of Snake Venom Phospholipase A2 Genes, An Application of FORS-D Analysis

  • DR Forsdyke
  • Mol Biol Evol
  • 1995
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