The joint effects of maternal prepregnancy body mass index and age on the risk of gastroschisis.

@article{SiegaRiz2009TheJE,
  title={The joint effects of maternal prepregnancy body mass index and age on the risk of gastroschisis.},
  author={Anna Maria Siega-Riz and Amy H. Herring and Andrew F. Olshan and Joanna Elizabeth Smith and Cynthia A. Moore},
  journal={Paediatric and perinatal epidemiology},
  year={2009},
  volume={23 1},
  pages={51-7}
}
Young maternal age has been associated with an increased risk of gastroschisis, while high maternal weight status has been associated with a decreased risk. We were interested in investigating the joint effect of these two risk factors to identify thresholds in risk associated with body mass index (BMI) for a given age. Data from the National Birth Defects Prevention Study included 464 case infants with gastroschisis and 4842 healthy controls. A generalised additive model with a bivariate… CONTINUE READING