The jaundice of the cell

  title={The jaundice of the cell},
  author={D. Greenberg},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  pages={15837 - 15839}
  • D. Greenberg
  • Published 2002
  • Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • “Fair is foul and foul is fair” (so say the witches in the opening scene of Macbeth ), and examples of this paradox abound in biology. Life-giving oxygen is also the source of cytotoxic oxidative stress; lethal gases like carbon monoxide are neurotransmitters that, among other things, facilitate reproduction (1). Another example is that of bilirubin, formerly dismissed as a waste product, whose image has been burnished by evolving evidence for a role in protecting cells from injury (2, 3). The… CONTINUE READING
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