The isolation of a 22 kDa band after SDS-PAGE of Schistosoma mansoni adult worms and its use to demonstrate that IgE responses against the antigen(s) it contains are associated with human resistance to reinfection.

@article{Dunne1997TheIO,
  title={The isolation of a 22 kDa band after SDS-PAGE of Schistosoma mansoni adult worms and its use to demonstrate that IgE responses against the antigen(s) it contains are associated with human resistance to reinfection.},
  author={David W. Dunne and M. N. Webster and Philip 3. Smith and J G Langley and Barbra Ann Richardson and Anthony J. C. Fulford and Anthony E. Butterworth and Robert F Sturrock and Henry Curtis Kariuki and John Henry Ouma},
  journal={Parasite immunology},
  year={1997},
  volume={19 2},
  pages={79-89}
}
In schistosomiasis endemic areas, intensities of reinfection after treatment are greater amongst young children than amongst adults, and high levels of parasite-specific IgE are associated with resistance to reinfection in an age-dependent manner. Previously we have reported that, in Western blots, a 22 kDa band was recognized by human IgE and that the incidence and intensity of S. mansoni reinfection were significantly lower amongst individuals who had IgE against this band, compared with… CONTINUE READING
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