The isolation and synthesis of 3-chloro-4-hydroxy-phenylacetamide produced by a plant-associated microfungus of the genus Xylaria

@article{Davis2005TheIA,
  title={The isolation and synthesis of 3-chloro-4-hydroxy-phenylacetamide produced by a plant-associated microfungus of the genus Xylaria},
  author={R. Davis and D. Watters and P. Healy},
  journal={Tetrahedron Letters},
  year={2005},
  volume={46},
  pages={919-921}
}
  • R. Davis, D. Watters, P. Healy
  • Published 2005
  • Chemistry
  • Tetrahedron Letters
  • Chemical investigations of the fermentation broth from the microfungus Xylaria sp. have afforded the new natural product 3-chloro-4-hydroxyphenylacetamide 1 and the previously reported fungal metabolite 3-chloro-4-hydroxyphenylacetic acid 2. This letter reports the isolation and full spectroscopic characterisation of compounds 1 and 2 by NMR, UV, IR and MS data. The crystal structure and one-pot synthesis of 3-chloro-4-hydroxyphenylacetamide are also reported. 
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