The isolation and sequence of canine interleukin-2.

  title={The isolation and sequence of canine interleukin-2.},
  author={Stephen P. Dunham and David John Argyle and David E. Onions},
  journal={DNA sequence : the journal of DNA sequencing and mapping},
  volume={5 3},
A cDNA corresponding to canine IL-2 has been isolated and sequenced. The cDNA was synthesised using RT-PCR, with oligonucleotide primers designed from conserved regions of published IL-2 sequences. The cDNA encodes a predicted full length IL-2 protein of 155 amino-acids. At the nucleic acid level, the canine cDNA shows 92, 88, 88, 82 and 74% homology to… CONTINUE READING