The isolation and characterization of missense mutants in the general repressor protein Ssn6 of Saccharomyces cerevisiae

Abstract

Ssn6, a TPR repeat-containing protein, associates with the Tup1 protein to form a general transcriptional repression complex in Saccharomyces cerevisiae. As part of a genetic analysis of this complex, we targeted mutations to the TPR repeat-coding region of the SSN6 gene, and applied selection for constitutive expression of the hypoxic gene ANB1. All but… (More)
DOI: 10.1007/s004380051189

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