The ionogenic nature of the secretory-granule membrane. Electrokinetic properties of isolated chromaffin granules.

@article{Matthews1972TheIN,
  title={The ionogenic nature of the secretory-granule membrane. Electrokinetic properties of isolated chromaffin granules.},
  author={E. K. Matthews and Richard J. Evans and Philip M. Dean},
  journal={The Biochemical journal},
  year={1972},
  volume={130 3},
  pages={825-32}
}
1. Chromaffin granules isolated from the bovine adrenal medulla possess an electrophoretic mobility of -1.12mum.s(-1).cm.V(-1), corresponding to a surface zeta potential of -14.4mV and surface charge density of 1.38x10(-6)C.cm(-2). 2. The mobility of chromaffin granules is pH-dependent, indicating an amphoteric surface with an isoelectric point at pH3.0 and… CONTINUE READING