The ionic dependence of black widow spider venom action at the stretch receptor neuron and neuromuscular junction of crustaceans.

Abstract

The effects of black widow spider venom (BWSV) on the crayfish stretch receptor and the lobster neuromuscular junction were examined. In crayfish stretch receptor neurons, BWSV caused a slight hyperpolarization followed by a large depolarization. The venom-induced depolarization of the stretch receptor was caused by an increase in membrane conductance to Na… (More)

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