The involvement of ventral tegmental area cholinergic muscarinic receptors in classically conditioned fear expression as measured with fear-potentiated startle.

@article{Greba2000TheIO,
  title={The involvement of ventral tegmental area cholinergic muscarinic receptors in classically conditioned fear expression as measured with fear-potentiated startle.},
  author={Quentin Greba and Logan Munro and Larry Kokkinidis},
  journal={Brain research},
  year={2000},
  volume={870 1-2},
  pages={135-41}
}
Accumulating evidence suggests that dopamine (DA) neurons in the ventral tegmental area (VTA) contribute to the complex amygdala-based neurocircuitry that mediates fear-motivated behaviors. Because of acetylcholine's (ACh) role in DA neuronal activation, the involvement of VTA cholinergic muscarinic receptors in Pavlovian conditioned fear responding was evaluated in the present study. Fear-potentiated startle was used to assess the effects of intraVTA infused methylscopolamine on conditioned… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-7 of 7 extracted citations

Involvement of the Mesocorticolimbic Dopaminergic System in Adaptive Behavior

Neuroscience and Behavioral Physiology • 2011
View 1 Excerpt

Dopamine is necessary for cue-dependent fear conditioning.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2009
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 23 references

Fibiger, Conditioned fear-induced changes in behavior with the expression of the immediate early gene c-fos: with or without diazepam pretreatment

H.C.C.H.M. Beck
J. Neurosci • 1995
View 1 Excerpt

Kindling of the mesolimbic dopamine by intracranial injections

D. C. Hoffman R. A Wise, A. Livermore Stevens
Synapse • 1992

The role of the amygdala in conditioned fear, in: J.P. Aggleton (Ed.), The Amygdala: Neurobiological Aspects of Emotion, Memory, and Mental Dysfunction, Wiley-Liss

M. Davis
New York, • 1992
View 3 Excerpts

appetitive and defensive behaviors

J. G. Pfaus J. R. Blackburn, A. G. Phillips, S. M. McGlynn, M. C. Olmstead, J. S. Yeomans
Prog . Neurobiol . • 1992

Ascending sensitivity are independent of the number of cells in the nucleus , afferent regulation of rat midbrain dopamine neurons

A. S. Freeman Kelland, L. A. Chiodo J. Rubin
Brain Res . Brain Res . Bull . • 1991

Similar Papers

Loading similar papers…