The involvement of the vasopressin system in stress-related disorders.

  title={The involvement of the vasopressin system in stress-related disorders.},
  author={Rainer Landgraf},
  journal={CNS & neurological disorders drug targets},
  volume={5 2},
The neuropeptide arginine vasopressin (AVP) is released within distinct brain areas upon appropriate stimulation, including stressful challenges. Following its predominantly dendritic release, AVP triggers a variety of receptor-mediated effects related to behavioral and neuroendocrine regulation. Antagonist treatment together with other sophisticated loss-of-function and gain-of-function approaches provide evidence for a multiple involvement of V1a and V1b receptor subtypes in stress-related… CONTINUE READING


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