The involvement of the monocytes/macrophages in chronic inflammation associated with atherosclerosis.

@article{Fenyo2013TheIO,
  title={The involvement of the monocytes/macrophages in chronic inflammation associated with atherosclerosis.},
  author={Ioana Madalina Fenyo and Anca Violeta Gafencu},
  journal={Immunobiology},
  year={2013},
  volume={218 11},
  pages={1376-84}
}
Atherosclerosis is a progressive chronic disease of large and medium arteries, characterized by the formation of atherosclerotic plaques. Monocytes and macrophages are key factors in lesion development, participating to the processes that mediate the progression of the atherosclerotic plaque (lipid accumulation, secretion of pro-inflammatory and cytotoxic factors, extracellular matrix remodeling). The recruitment of the monocytes in the vascular wall represents a hallmark in the pathology of… CONTINUE READING

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