The involvement of the cerebellum in amyotrophic lateral sclerosis.

@article{Prell2013TheIO,
  title={The involvement of the cerebellum in amyotrophic lateral sclerosis.},
  author={Tino Prell and Julian Grosskreutz},
  journal={Amyotrophic lateral sclerosis & frontotemporal degeneration},
  year={2013},
  volume={14 7-8},
  pages={
          507-15
        }
}
Amyotrophic lateral sclerosis is a multisystemic neurodegenerative disease in which degenerative processes are not exclusively restricted to the upper and lower motor neurons. Herein, imaging and neuropathological evidence for involvement of the cerebellum, which to date is not thought to be involved in ALS, is reviewed. Evidence for involvement of the cerebellum in ALS comes from several neuropathological studies. Especially ubiquitinated forms of TDP-43 and ubiquitinated p62-positive… CONTINUE READING
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