The involvement of the Schizosaccharomyces pombe sep9/spt8 gene in the regulation of septum cleavage.

@article{Batta2009TheIO,
  title={The involvement of the Schizosaccharomyces pombe sep9/spt8 gene in the regulation of septum cleavage.},
  author={Gyula Batta and Zsolt Szil{\'a}gyi and Miklos Laczik and Matthias Sipiczki},
  journal={FEMS yeast research},
  year={2009},
  volume={9 5},
  pages={757-67}
}
Schizosaccharomyces cells divide by medial septation, followed by enzymatic degradation of parts of the septum (septum cleavage) to allow the sister cells to separate from each other. In a previous study we found that the cell separation mutant sep9-307 was defective in a gene that encodes a protein highly similar in sequence to the Saccharomyces cerevisiae protein Spt8, a subunit of the SAGA complex. Here, we show that the sep9-307 mutation causes a frameshift in translation. The deletion of… CONTINUE READING