The involvement of several enzymes in methanol detoxification in Drosophila melanogaster adults.

@article{Wang2013TheIO,
  title={The involvement of several enzymes in methanol detoxification in Drosophila melanogaster adults.},
  author={Shu-ping Wang and Xing-Xing Hu and Qingwei Meng and Shahid Arain Muhammad and Rui-rui Chen and Fei Li and Guoqing Li},
  journal={Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology},
  year={2013},
  volume={166 1},
  pages={7-14}
}
Methanol is among the most common short-chain alcohols in fermenting fruits, the natural food and oviposition sites of the fruit fly Drosophila melanogaster. Our previous results showed that cytochrome P450 monooxygenases (CYPs) were associated with methanol detoxification in the larvae. Catalases, alcohol dehydrogenases (ADHs), esterases (ESTs) and glutathione S-transferases (GSTs) were specifically inhibited by 3-amino-1,2,4-triazole (3-AT), 4-methylpyrazole (4-MP), triphenyl phosphate (TPP… CONTINUE READING
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