The involvement of genetic polymorphism of IL-10 promoter in non-small cell lung cancer.

@article{Shih2005TheIO,
  title={The involvement of genetic polymorphism of IL-10 promoter in non-small cell lung cancer.},
  author={C. -M. Shih and Yao-Ling Lee and H M Chiou and Wei-Fang Hsu and Wei-Erh Chen and M P Chou and L Lin},
  journal={Lung cancer},
  year={2005},
  volume={50 3},
  pages={291-7}
}
STUDY OBJECTIVES Interleukin-10 (IL-10) is mainly an anti-inflammatory cytokine produced by a number of cells including normal and neoplastic cells and has been implicated in autoimmunity, transplantation tolerance and tumorigenesis. Inter-individual variations in IL-10 production were genetically contributed to polymorphisms within IL-10 promoter region. The aim of this study was to determine whether polymorphisms in the IL-10 gene promoter were involved in predisposing an individual to non… CONTINUE READING

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