The involvement of Ca2+ and integrins in directional responses of zebrafish keratocytes to electric fields.

@article{Huang2009TheIO,
  title={The involvement of Ca2+ and integrins in directional responses of zebrafish keratocytes to electric fields.},
  author={Ling Huang and Peter Cormie and Mark Alan Messerli and Kenneth R. Robinson},
  journal={Journal of cellular physiology},
  year={2009},
  volume={219 1},
  pages={
          162-72
        }
}
Many cells respond directionally to small DC electrical fields (EFs) by an unknown mechanism, but changes in intracellular Ca(2+) are widely assumed to be involved. We have used zebrafish (Danio rerio) keratocytes in an effort to understand the nature of the EF-cell interaction. We find that the adult zebrafish integument drives substantial currents outward through wounds produced by scale removal, establishing that keratocytes near the wound will experience endogenous EFs. Isolated keratocytes… CONTINUE READING
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