The invertebrate growth factor/CECR1 subfamily of adenosine deaminase proteins.

@article{Charlab2001TheIG,
  title={The invertebrate growth factor/CECR1 subfamily of adenosine deaminase proteins.},
  author={Rosane Charlab and Jesus G Valenzuela and Jackie Andersen and Jo{\~a}o Meireles Ribeiro},
  journal={Gene},
  year={2001},
  volume={267 1},
  pages={
          13-22
        }
}
  • Rosane Charlab, Jesus G Valenzuela, +1 author João Meireles Ribeiro
  • Published in Gene 2001
  • Biology, Medicine
  • Adenosine deaminase (ADA) catalyzes the hydrolysis of adenosine to inosine. Its lack determines severe combined immunodeficiency in mammals, possibly due to accumulation of extracellular adenosine, which induces apoptosis in lymphocytes (Franco et al., 1998). Thus, presence of normal levels of ADA leads to normal growth and proliferation of lymphocytes. Several vertebrate and microbial ADA amino-acid sequences are known, with substantial similarity to each other. On the other hand, there are… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 15 CITATIONS

    Phylogenetic Analysis Reveals a Novel Protein Family Closely Related to Adenosine Deaminase

    VIEW 6 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    The emerging role of adenosine deaminases in insects.

    VIEW 4 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Immunogenicity and Serological Cross-Reactivity of Saliva Proteins among Different Tsetse Species

    VIEW 1 EXCERPT
    CITES BACKGROUND

    Impact of uremic environment on peritoneum: a proteomic view.

    VIEW 1 EXCERPT
    CITES BACKGROUND

    Proteomic analysis of porcine saliva.

    VIEW 2 EXCERPTS
    CITES BACKGROUND