The invertebrate B(0) system transporter, D. melanogaster NAT1, has unique d-amino acid affinity and mediates gut and brain functions.

@article{Miller2008TheIB,
  title={The invertebrate B(0) system transporter, D. melanogaster NAT1, has unique d-amino acid affinity and mediates gut and brain functions.},
  author={Melissa M. Miller and Lyudmila B. Popova and Ella A. Meleshkevitch and Philip V Tran and Dmitri Y. Boudko},
  journal={Insect biochemistry and molecular biology},
  year={2008},
  volume={38 10},
  pages={923-31}
}
The CG3252 gene product, DmNAT1, represents the first Nutrient Amino acid Transporter cloned from Drosophila. It absorbs a broader set of neutral amino acids versus earlier characterized insect NATs and mammalian NATs-B(0) system transporters from the Sodium Neurotransmitter symporter Family (SNF, a.k.a. solute carrier family 6, SLC6). In addition to B(0)-specific l-substrates, DmNAT1 equally or more effectively transports d-amino acids with sub-millimolar affinities and 1:1 sodium:amino acid… CONTINUE READING
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