The invasiveness of five medulloblastoma cell lines in collagen gels

  title={The invasiveness of five medulloblastoma cell lines in collagen gels},
  author={Adrianna Ranger and Warren Mcdonald and Emi Moore and Rolando F. DelMaestro},
  journal={Journal of Neuro-Oncology},
Local recurrence continues to limit survival in medulloblastoma patients, largely related to the persistence of invasive cells at the site of tumour resection and leptomeningeal dissemination. Given the relative dearth of understanding of causative mechanisms behind the invasiveness of medulloblastomas, and a general lack of validated in vitro models with which to study them, our objectives were (1) to obtain quantitative data on the invasiveness of five distinct medulloblastoma cell lines… CONTINUE READING


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