The inv(11)(p15q22) chromosome translocation of therapy-related myelodysplasia with NUP98-DDX10 and DDX10-NUP98 fusion transcripts.

@article{Ikeda1999TheIC,
  title={The inv(11)(p15q22) chromosome translocation of therapy-related myelodysplasia with NUP98-DDX10 and DDX10-NUP98 fusion transcripts.},
  author={Takanori Ikeda and Kazuhiko Ikeda and Ko Sasaki and Keiki Kawakami and Jiro Takahara},
  journal={International journal of hematology},
  year={1999},
  volume={69 3},
  pages={160-4}
}
Chromosomal abnormalities involving the 11p15 or 11q22-23 bands have been reported in several types of human neoplasms including hematopoietic malignancies. The abnormalities are observed in therapy-related malignancies and less frequently in de novo myeloid malignancies. Abnormality of the MLL gene located on chromosome 11q23 has been well known in therapy-related myeloid malignancies, but it has been reported only recently that the inv(11)(p15q22) in de novo or therapy-related myeloid… CONTINUE READING

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