The intracellular pH of the thermophilic bacterium Thermoanaerobacter wiegelii during growth and production of fermentation acids

@article{Cook2000TheIP,
  title={The intracellular pH of the thermophilic bacterium Thermoanaerobacter wiegelii during growth and production of fermentation acids},
  author={Gregory. M. Cook},
  journal={Extremophiles},
  year={2000},
  volume={4},
  pages={279-284}
}
The thermophilic glycolytic anaerobe Thermoanaerobacter wiegelii grows over the pH range 5.1–7.7, and no growth is observed below pH 5.0 or above 7.7. When T. wiegelii was grown in pH-uncontrolled batch culture, glucose was fermented to ethanol, acetate, and lactate. Small amounts of lactic acid were produced once the external pH reached 6.0, and a fructose-1,6-diphosphate (FDP) activated lactate dehydrogenase (LDH) was detected in cell-free crude extracts. Maximal activation of LDH by FDP was… CONTINUE READING
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Carbohydrate utilization by Clostridium thermocellum: importance of internal pH in regulating growth

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  • Enzyme Microb Technol
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