The intracellular life of Cryptococcus neoformans.

  title={The intracellular life of Cryptococcus neoformans.},
  author={Carolina Coelho and Anam{\'e}lia Lorenzetti Bocca and Arturo Casadevall},
  journal={Annual review of pathology},
Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological studies of human populations show a high prevalence of human infection, which rarely progresses to disease in immunocompetent hosts. However, decreased host immunity places individuals at high risk for cryptococcal disease. The disease can result from acute infection or reactivation of latent infection, in which yeasts within granulomas and host macrophages emerge to cause disease. In this review, we summarize… CONTINUE READING
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