The interplay between morphogens and tissue growth.

  title={The interplay between morphogens and tissue growth.},
  author={Andr{\'e}s Dekanty and Marco Mil{\'a}n},
  journal={EMBO reports},
  volume={12 10},
Morphogens are conserved, secreted signalling molecules that regulate the size, shape and patterning of animal tissues and organs. Recent experimental evidence has emphasized the fundamental role of tissue growth in expanding the expression domains of morphogens and their target genes, in generating morphogen gradients and in modulating the response of cells to morphogens. Moreover, the classic view of how morphogens, particularly through their concentration gradient, regulate tissue size… CONTINUE READING