The interplay between mitochondrial dynamics and mitophagy.

@article{Twig2011TheIB,
  title={The interplay between mitochondrial dynamics and mitophagy.},
  author={Gilad Twig and Orian S Shirihai},
  journal={Antioxidants & redox signaling},
  year={2011},
  volume={14 10},
  pages={1939-51}
}
Mitochondrial dynamics and mitophagy are recognized as two critical processes underlying mitochondrial homeostasis. Morphological and bioenergetic characterization of the life cycle of an individual mitochondrion reveals several points where fusion, fission, and mitophagy interact. Mitochondrial fission can produce an impaired daughter unit that will be targeted by the autophagic machinery. Mitochondrial fusion, on the other hand, may serve to dilute impaired respiratory components and thereby… CONTINUE READING
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