The interplay between genome and network evolution in eukaryotes

@inproceedings{Fokkens2013TheIB,
  title={The interplay between genome and network evolution in eukaryotes},
  author={Like Fokkens},
  year={2013}
}
We assume that the functional relations that a protein engages in, influences it’s evolutionary dynamics. An extreme case is a functional module in which all components are strongly dependent on each other, for example a protein complex or metabolic pathway. If a protein’s function is only relevant on the level of the module, selection will act on module level as well. This leads to distinct phylogenetic patterns: either the module is completely present or completely absent. In other words, the… CONTINUE READING

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