The internalization of posterior subcapsular cataracts (PSCs) in Royal College of Surgeons (RCS) rats. II. The inter-relationship of optical quality and structure as a function of age.

@article{Kuszak1999TheIO,
  title={The internalization of posterior subcapsular cataracts (PSCs) in Royal College of Surgeons (RCS) rats. II. The inter-relationship of optical quality and structure as a function of age.},
  author={Jer R. Kuszak and K J Al-ghoul and Layne A. Novak and K Linnea Peterson and K L Herbert and Jacob Gershon Sivak},
  journal={Molecular vision},
  year={1999},
  volume={5},
  pages={7}
}
PURPOSE The Royal College of Surgeons (RCS) rat is an animal model for human retinal degenerative disease and posterior subcapsular cataracts (PSCs). The purpose of this study was to correlate the structure and optical quality of RCS lenses with PSCs as a function of their internalization, with normal, non-cataractous, age-matched control lenses. METHODS Correlative light (LM), scanning electron microscopic (SEM), three-dimensional computer assisted drawings (3D-CADs) and low power helium… CONTINUE READING