The internal anal sphincter: mechanisms of control and its role in maintaining anal continence.

@article{Penninckx1992TheIA,
  title={The internal anal sphincter: mechanisms of control and its role in maintaining anal continence.},
  author={Freddy M. Penninckx and B{\'e}la Lest{\'a}r and Raymond P. Kerremans},
  journal={Bailliere's clinical gastroenterology},
  year={1992},
  volume={6 1},
  pages={193-214}
}
The human IAS has particular structural and functional characteristics. This smooth muscle constantly generates rhythmic electrical slow waves, but no action potentials. The slow waves are linked to calcium fluxes and both are essential for mechanical activity, i.e. the ASPW. The IAS is pharmacologically characterized by the presence of alpha excitatory and… CONTINUE READING