The intermediate filament protein nestin is expressed in the developing kidney and heart and might be regulated by the Wilms ’ tumor suppressor Wt 1

@inproceedings{Wagner2006TheIF,
  title={The intermediate filament protein nestin is expressed in the developing kidney and heart and might be regulated by the Wilms ’ tumor suppressor Wt 1},
  author={Nicole Wagner and Kay-Dietrich Wagner and Holger Scholz and Karl Kirschner and Andreas Schedl},
  year={2006}
}
Nestin is an intermediate filament protein originally described in neural stem cells and a variety of progenitor cells. More recently, nestin was detected in rat kidney podocytes. We show here that nestin is expressed in a developmentally regulated pattern in the kidney. Nestin was detected by immunohistochemistry in the condensing mesenchyme surrounding the ureter, in developing glomeruli, in podocytes of the adult kidney, and in a podocyte cell line. Nestin shared a strikingly overlap in… CONTINUE READING

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