The interleukin-6-572G/C gene polymorphism and the risk of intracranial aneurysms in a Chinese population.

@article{Liu2012TheIG,
  title={The interleukin-6-572G/C gene polymorphism and the risk of intracranial aneurysms in a Chinese population.},
  author={Yi Liu and Jidong Sun and Cong Wu and Xudong Cao and Min He and Chao You},
  journal={Genetic testing and molecular biomarkers},
  year={2012},
  volume={16 7},
  pages={822-6}
}
Interleukin-6 (IL-6) is an important proinflammatory cytokine that plays an important role in the pathogenesis of intracranial aneurysms (IAs). The aim of this study was to investigate the association between the IL-6-572G/C polymorphism and the risk of IAs in a Chinese population. The IL-6-572G/C gene polymorphisms in 220 IA cases and 220 controls were analyzed using the polymerase chain reaction-restriction fragment length polymorphism method. The IL-6-572GG (odds ratio [OR]=3.35, 95… CONTINUE READING