The interleukin-1 cluster gene region is associated with multiple sclerosis in an Italian Caucasian population.


BACKGROUND Polymorphisms of the interleukin-1 (IL-1) gene family have been proposed as potential variants for different diseases including multiple sclerosis (MS). With respect to MS, IL-1 beta (-511 C/T; rs16944), IL-1 beta (+3954 C/T; rs1143634), IL-1 alpha (-889 C/T; rs1800587), IL-1 alpha (+4845 G/T; rs17561), and the variable number of tandem repeats… (More)
DOI: 10.1111/j.1468-1331.2010.02952.x