The interactive effects of hepatic lipase gene promoter polymorphisms with sex and obesity on high-density-lipoprotein cholesterol levels in Taiwanese-Chinese.

@article{Ko2004TheIE,
  title={The interactive effects of hepatic lipase gene promoter polymorphisms with sex and obesity on high-density-lipoprotein cholesterol levels in Taiwanese-Chinese.},
  author={Yu-Lin Ko and L Hsu and Kuang-Hung Hsu and Yu-Hsien Ko and Ying-Shiung Lee},
  journal={Atherosclerosis},
  year={2004},
  volume={172 1},
  pages={135-42}
}
OBJECTIVES Hepatic lipase (HL) is involved in the metabolism of several lipoproteins and plays a key role in reverse cholesterol transport. The aim of the current study was to test the statistical association between two HL gene promoter polymorphisms (HL-514C/T and HL-250G/A) and lipoprotein profiles in a Taiwanese-Chinese population. METHODS A sample population of 716 Taiwanese-Chinese individuals was analyzed. DNA was extracted from the blood and genotypes were determined by polymerase… CONTINUE READING

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