The interaction of enkephalins with substance P on vascular smooth muscle.

  • Alfreg F. Moore
  • Published 1979 in
    Research communications in chemical pathology and…


Interactions between SP and the enkephalins have bben reported in the CNS, and the possibility of a more peripheral site of interaction has now been investigated. SP (10(-6) - 10(-4) g/ml) induced dose-related contractions of the rabbit isolated aorta, which were resistant to alpha-adrenoceptor blockade (phentolamine, 5 x 10(-6) g/ml). Neither met- nor leu… (More)


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