The interaction of dietary carotenoids with radical species.

  title={The interaction of dietary carotenoids with radical species.},
  author={Alan Mortensen and Leif H. Skibsted and T George Truscott},
  journal={Archives of biochemistry and biophysics},
  volume={385 1},
Dietary carotenoids react with a wide range of radicals such as CCl3O2*, RSO2*, NO2*, and various arylperoxyl radicals via electron transfer producing the radical cation of the carotenoid. Less strongly oxidizing radicals, such as alkylperoxyl radicals, can lead to hydrogen atom transfer generating the neutral carotene radical. Other processes can also arise such as adduct formation with sulphur-centered radicals. The oxidation potentials have been established, showing that, in Triton X-100… 

Oxo-Carotenoids as Efficient Superoxide Radical Scavengers

Oxo-carotenoids containing conjugated carbonyl groups in their chains were designed to be more efficient superoxide radical scavengers than natural carotenoids, β-carotene and canthaxanthin. A

Antioxidative Reaction of Carotenes against Peroxidation of Fatty Acids Initiated by Nitrogen Dioxide: A Theoretical Study.

It is found that for CARs ET is more likely to occur in the most polar environment than are HAT and RAF, and LYC is a more effective antioxidative agent against NO2(•)-initiated lipid peroxidation than is β-CAR.

Anti- and pro-oxidative mechanisms comparing the macular carotenoids zeaxanthin and lutein with other dietary carotenoids - a singlet oxygen, free-radical in vitro and ex vivo study.

  • Fritz BoehmR. EdgeT. G. Truscott
  • Chemistry, Physics
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
  • 2020
It is shown that the mechanistic role of oxygen differs very significantly for anti-/pro-oxidation by hydroxyl radicals when compared to nitrogen dioxide.

Interactions between Carotenoids from Marine Bacteria and Other Micronutrients: Impact on Stability and Antioxidant Activity

Combining antioxidants acting via complementary mechanisms could be the key for optimizing the activity of this bacterial carotenoid cocktail.

Scavenging of Benzylperoxyl Radicals by Carotenoids

It is demonstrated that carotenoids react with peroxyl radicals only slightly more reactive than lipidperoxyl radical neither by electron transfer nor by hydrogen atom donation, but by adduct formation.

A marginal contribution of selected carotenoids to the supression of UV -irradiation -induced lecithin peroxidation in hexane solution

The aim of this work was to study the anticipated antioxidant role of four se- lected carotenoids in mixtures with lecithin lipoidal compounds in hexane solution, un- der continuous UV-irradiation in

Spin-trapping studies on the reaction of NO2 with β-carotene

Absorption spectrophotometric studies indicated that in chloroform β-carotene reacted with NO2 with a stoichiometry of 1:2. To understand the reaction mechanism, free radical intermediates produced

Electron Donation Mechanisms of β‐Carotene as a Free Radical Scavenger

ABSTRACT The free radical scavenging ability of β-carotene was studied using free radical 2,2-diphenyl-1-picryl-hydrazyl (DPPH). As the concentration of β-carotene in acetone increased, the



Importance of carotenoid structure in radical-scavenging reactions

The rate of (parallel) reaction between carotenoids and phenoxyl radical to yield (i) carotenoid/phenoxyl adducts and (ii) carotenoid radical cations (in effect regenerating the phenol by reduction)

Antioxidant reactions of beta-carotene: identification of carotenoid-radical adducts.

These product structures provide the first mechanistic explanation for the radical scavenging reactions of carotenoids.

Scavenging of Nitrogen Dioxide, Thiyl, and Sulfonyl Free Radicals by the Nutritional Antioxidant -Carotene (*)

Mechanisms of free radical scavenging by the nutritional antioxidant β-carotene have been investigated by pulse radiolysis and rate constants for thiyl radical-addition reactions vary from 106 to 109M s and correlate with the lipophilicity of the thiyle radical under study.

Re-appraisal of the tocopheroxyl radical reaction with beta-carotene: evidence for oxidation of vitamin E by the beta-carotene radical cation.

Steady-state radiolysis experiments confirmed that alpha-tocopherol protects beta-carotene from oxidation by hexane radicals and no evidence was obtained for a slower rate of beta- carotene radical cation formation in beta-Carotene/alpha-tocopheroxyl mixtures resulting from alpha-tocopherol radical oxidation of Beta-carotsene.

beta-Carotene: an unusual type of lipid antioxidant.

New experiments in vitro show that beta-carotene belongs to a previously unknown class of biological antioxidants, and exhibits good radical-trapping antioxidant behavior only at partial pressures of oxygen significantly less than 150 torr, the pressure of oxygen in normal air.

Carotenoid cation radicals: electrochemical, optical, and EPR study

The general aim of this investigation is to determine whether carotenoid cation radicals can be produced, and stabilized, electrochemically. Hence, the authors have undertaken a detailed study of the

Kinetics of parallel electron transfer from beta-carotene to phenoxyl radical and adduct formation between phenoxyl radical and beta-carotene.

Phenoxyl radicals generated by laser flash photolysis were found to react with beta-carotene with concomitant beta-Carotene bleaching in two parallel reactions with similar rates, and may prove important for an understanding of how beta- carotene acts as an antioxidant.