The interaction of copper (Cu++) with the erythrocyte membrane and 2,3-dimercaptopropanesulphonate in vitro: a source of activated oxygen species.

Abstract

The therapy of copper poisoning and of Wilson's disease with 2,3-dimercaptopropane-1-sulphonate (DMPS) may increase the copper-induced haemolysis. Some aspects of the mechanism of this effect were investigated. The possible generation of activated oxygen species during the interaction of Cu++ and DMPS was studied using a chemiluminescent method detecting… (More)

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@article{Aaseth1987TheIO, title={The interaction of copper (Cu++) with the erythrocyte membrane and 2,3-dimercaptopropanesulphonate in vitro: a source of activated oxygen species.}, author={Jan Olav Aaseth and Stefan R. Ribarov and Pavel Bochev}, journal={Pharmacology & toxicology}, year={1987}, volume={61 4}, pages={250-3} }