The interaction of agouti signal protein and melanocyte stimulating hormone to regulate melanin formation in mammals.

@article{Furumura1996TheIO,
  title={The interaction of agouti signal protein and melanocyte stimulating hormone to regulate melanin formation in mammals.},
  author={Minao Furumura and Chikara Sakai and Zalfa A Abdel-Malek and Gregory S Barsh and Vincent J. Hearing},
  journal={Pigment cell research},
  year={1996},
  volume={9 4},
  pages={191-203}
}
Important regulatory controls of melanogenesis that operate at the subcellular level to modulate the structural and/or the functional nature of the melanins and melanin granules produced in melanocytes are reviewed. Melanocyte stimulating hormone and agouti signal protein have antagonistic roles and possibly opposing mechanisms of action in the melanocyte. In the mouse, melanocyte stimulating hormone promotes melanogenic enzyme function and elicits increases in the amount of eumelanins produced… CONTINUE READING

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